You can obtain Citrulline from food, especially watermelons, and it can be also manufactured from ornithine, in the body‚ urea cycle. This cycle helps rid your body of ammonia, a waste product of protein digestion.
After your digestive system metabolizes citrulline malate into citrulline, enzymes in your liver cells convert it into arginine, then into nitric oxide in a process that also produces new citrulline molecules. Nitric oxide is well known for its function as a vasodilator. Supplementing L-citrulline also increases ornithine and arginine plasma content.
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